GRHL2 monoclonal antibody, clone CL3760
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin shows strong nuclear positivity in epithelial cells.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human GRHL2.
Immunogen
Recombinant protein corresponding to human GRHL2.
Epitope
This antibody binds to an epitope located within the peptide sequence VVKAEDFTPV as determined by overlapping synthetic peptides.
Sequence
NRVQVLKTVPVNLSLNQDHLENSKREQYSISFPESSAIIPVSGITVVKAEDFTPVFMAPPVHYPRGDGEEQRVVIFEQTQYDVPSLATHSAYLKDDQRSTPDSTYSESFKDAATEKFRSASVGAEEYMYDQTSSGTFQYTLEATKSLRQK
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:5000-1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin shows strong nuclear positivity in epithelial cells. -
Gene Info — GRHL2
Entrez GeneID
79977Protein Accession#
Q6ISB3Gene Name
GRHL2
Gene Alias
BOM, DFNA28, FLJ11172, FLJ13782, MGC149294, MGC149295, TFCP2L3
Gene Description
grainyhead-like 2 (Drosophila)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28)
Other Designations
transcription factor CP2-like 3
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Disease
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