WHSC1 monoclonal antibody, clone CL1063
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with WHSC1 monoclonal antibody, clone CL1063 (Cat # MAB15663).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with WHSC1 monoclonal antibody, clone CL1063 (Cat # MAB15663) shows nuclear positivity in the reaction centrum cells.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human WHSC1.
Immunogen
Recombinant protein corresponding to human WHSC1.
Epitope
This antibody binds to an epitope located within the peptide sequence ALPFIPADKL as determined by overlapping synthetic peptides.
Sequence
SANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGD
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG2b
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with WHSC1 monoclonal antibody, clone CL1063 (Cat # MAB15663).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with WHSC1 monoclonal antibody, clone CL1063 (Cat # MAB15663) shows nuclear positivity in the reaction centrum cells. -
Gene Info — WHSC1
Entrez GeneID
7468Protein Accession#
O96028Gene Name
WHSC1
Gene Alias
FLJ23286, KIAA1090, MGC176638, MMSET, NSD2, REIIBP, TRX5, WHS
Gene Description
Wolf-Hirschhorn syndrome candidate 1
Omim ID
602952Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq
Other Designations
IL5 promoter REII region-binding protein|OTTHUMP00000149955|OTTHUMP00000159146|Wolf-Hirschhorn syndrome candidate 1 protein|multiple myeloma SET domain containing protein type III|trithorax/ash1-related protein 5
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Interactome
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Pathway
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Disease
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