NAPRT1 monoclonal antibody, clone CL0665
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human NAPRT1.
Immunogen
Recombinant protein corresponding to human NAPRT1.
Epitope
This antibody binds to an epitope located within the peptide sequence PAFFEHLRALDCSEV as determined by overlapping synthetic peptides.
Sequence
PAFFEHLRALDCSEVTVRALPEGSLAFPGVPLLQVSGPLLVVQLLETPLLCLVSYASLVATNAARLRLIAGP
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human liver tissue lysate with NAPRT1 monoclonal antibody, clone CL0665 (Cat # MAB15654).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with NAPRT1 monoclonal antibody, clone CL0665 (Cat # MAB15654) shows strong cytoplasmic immunoreactivity in renal tubules. -
Gene Info — NAPRT1
Entrez GeneID
93100Protein Accession#
Q6XQN6Gene Name
NAPRT1
Gene Alias
PP3856
Gene Description
nicotinate phosphoribosyltransferase domain containing 1
Omim ID
611552Gene Ontology
HyperlinkGene Summary
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM
Other Designations
nicotinic acid phosphoribosyltransferase
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