SLC22A2 monoclonal antibody, clone CL0628
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human SLC22A2.
Immunogen
Recombinant protein corresponding to human SLC22A2.
Epitope
This antibody binds to an epitope located within the peptide sequence KNAEAMRIIKHIAKK as determined by overlapping synthetic peptides.
Sequence
ESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIR
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with SLC22A2 monoclonal antibody, clone CL0628 (Cat # MAB15641) shows strong immunoreactivity in renal tubules. -
Gene Info — SLC22A2
Entrez GeneID
6582Protein Accession#
O15244Gene Name
SLC22A2
Gene Alias
MGC32628, OCT2
Gene Description
solute carrier family 22 (organic cation transporter), member 2
Omim ID
602608Gene Ontology
HyperlinkGene Summary
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq
Other Designations
OTTHUMP00000017538|organic cation transporter (OCT2)|organic cation transporter 2|solute carrier family 22 member 2
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Interactome
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