USP46 monoclonal antibody, clone CL0363
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with USP46 monoclonal antibody, clone CL0363 (Cat # MAB15615).
Immunofluorescence
Immunofluorescent staining of U-2 OS cells with USP46 monoclonal antibody, clone CL0363 (Cat # MAB15615) (Green) shows specific staining in nucleoli. Microtubule and nuclear probes are visualized in red and blue, respectively (where available).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human USP46.
Immunogen
Recombinant protein corresponding to human USP46.
Epitope
This antibody binds to an epitope located within the peptide sequence TNETRCLNCE as determined by overlapping synthetic peptides.
Sequence
LFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG2b
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with USP46 monoclonal antibody, clone CL0363 (Cat # MAB15615).Immunofluorescence
Immunofluorescent staining of U-2 OS cells with USP46 monoclonal antibody, clone CL0363 (Cat # MAB15615) (Green) shows specific staining in nucleoli. Microtubule and nuclear probes are visualized in red and blue, respectively (where available). -
Gene Info — USP46
Entrez GeneID
64854Protein Accession#
P62068Gene Name
USP46
Gene Alias
FLJ11850, FLJ12552, FLJ14283, FLJ39393
Gene Description
ubiquitin specific peptidase 46
Gene Ontology
HyperlinkGene Summary
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM
Other Designations
ubiquitin specific protease 46
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Interactome
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Disease
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