FLT1 monoclonal antibody, clone CL0345
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of RT-4 cell lysate with FLT1 monoclonal antibody, clone CL0345 (Cat # MAB15610).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human fallopian tube with FLT1 monoclonal antibody, clone CL0345 (Cat # MAB15610) shows strong immunoreactivity in the endothelial cells.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human FLT1.
Immunogen
Recombinant protein corresponding to human FLT1.
Epitope
This antibody binds to an epitope located within the peptide sequence EPQITWFKNN as determined by overlapping synthetic peptides.
Sequence
LNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVYHCKATNQKGS
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG2b
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of RT-4 cell lysate with FLT1 monoclonal antibody, clone CL0345 (Cat # MAB15610).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human fallopian tube with FLT1 monoclonal antibody, clone CL0345 (Cat # MAB15610) shows strong immunoreactivity in the endothelial cells. -
Gene Info — FLT1
Entrez GeneID
2321Protein Accession#
P17948Gene Name
FLT1
Gene Alias
FLT, VEGFR1
Gene Description
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
Omim ID
165070Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia
Other Designations
fms-related tyrosine kinase 1|soluble VEGF receptor 1-14|soluble VEGFR1 variant 2|soluble VEGFR1 variant 21|vascular endothelial growth factor/vascular permeability factor receptor
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Interactome
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Pathway
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Disease
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