SCGN monoclonal antibody, clone CL0271
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant human SCGN.
Immunogen
Recombinant protein corresponding to human SCGN.
Sequence
RDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLK
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:2500-1:5000)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human brain tissue lysate with SCGN monoclonal antibody, clone CL0271 (Cat # MAB15585).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with SCGN monoclonal antibody, clone CL0271 (Cat # MAB15585) shows strong cytoplasmic and nuclear immunoreactivity in the islets of Langerhans. -
Gene Info — SCGN
Entrez GeneID
10590Protein Accession#
O76038Gene Name
SCGN
Gene Alias
CALBL, DJ501N12.8, SECRET, SEGN, setagin
Gene Description
secretagogin, EF-hand calcium binding protein
Omim ID
609202Gene Ontology
HyperlinkGene Summary
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq
Other Designations
OTTHUMP00000016124|calbindin-like|secretagogin
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Interactomes
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Publication Reference
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Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human.
Shi TJ, Xiang Q, Zhang MD, Tortoriello G, Hammarberg H, Mulder J, Fried K, Wagner L, Josephson A, Uhlen M, Harkany T, Hokfelt T.
Molecular Pain 2012 Oct; 8:80.
Application:IF, IHC-Fr, WB-Ti, Human, Mouse, Rat, Spinal cords.
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Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human.
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