EMD monoclonal antibody, clone CL0203
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human EMD.
Immunogen
Recombinant protein corresponding to human EMD.
Epitope
This antibody binds to an epitope located within the peptide sequence QSKGYNDDYY as determined by overlapping synthetic peptides.
Sequence
ASSYSFSDLNSTRGDADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDADAFHHQVHDDDLLSSSEEECKDRERPMYGRDSACQSITHY
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:5000-1:10000)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of RT-4 cell lysate with EMD monoclonal antibody, clone CL0203 (Cat # MAB15560).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with EMD monoclonal antibody, clone CL0203 (Cat # MAB15560) shows strong nuclear membrane positivity in the epidermis cells.Immunofluorescence
Immunofluorescent staining of HeLa cells with EMD monoclonal antibody, clone CL0203 (Cat # MAB15560) (Green) shows a distinct nuclear membranous pattern with a weaker additional ER. Microtubule and nuclear probes are visualized in red and blue respectively (where available). -
Gene Info — EMD
Entrez GeneID
2010Protein Accession#
P50402Gene Name
EMD
Gene Alias
EDMD, LEMD5, STA
Gene Description
emerin
Gene Ontology
HyperlinkGene Summary
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq
Other Designations
LEM domain containing 5|OTTHUMP00000031938|OTTHUMP00000061687
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Interactome
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Pathway
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Disease
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