ARG1 monoclonal antibody, clone CL0186
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human liver tissue lysate with ARG1 monoclonal antibody, clone CL0186 (Cat # MAB15555).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with ARG1 monoclonal antibody, clone CL0186 (Cat # MAB15555) shows strong nuclear and cytoplasmic positivity in hepatocytes.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ARG1.
Immunogen
Recombinant protein corresponding to human ARG1.
Epitope
This antibody binds to an epitope located within the peptide sequence KGQPRGGVEE as determined by overlapping synthetic peptides.
Sequence
TIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:2500-1:5000)
Western Blot (1:1000-1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human liver tissue lysate with ARG1 monoclonal antibody, clone CL0186 (Cat # MAB15555).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with ARG1 monoclonal antibody, clone CL0186 (Cat # MAB15555) shows strong nuclear and cytoplasmic positivity in hepatocytes. -
Gene Info — ARG1
Entrez GeneID
383Protein Accession#
P05089Gene Name
ARG1
Gene Alias
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Gene Description
arginase, liver
Gene Ontology
HyperlinkGene Summary
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq
Other Designations
A-I|OTTHUMP00000017209|arginase, type I
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Interactome
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Pathway
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Disease
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