AQP4 monoclonal antibody, clone CL0178
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with AQP4 monoclonal antibody, clone CL0178 (Cat # MAB15552).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum with AQP4 monoclonal antibody, clone CL0178 (Cat # MAB15552) shows strong immunoreactivity in the molecular layer.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human AQP4.
Immunogen
Recombinant protein corresponding to human AQP4.
Epitope
This antibody binds to an epitope located within the peptide sequence FKRRFKEAFS as determined by overlapping synthetic peptides.
Sequence
CPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with AQP4 monoclonal antibody, clone CL0178 (Cat # MAB15552).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum with AQP4 monoclonal antibody, clone CL0178 (Cat # MAB15552) shows strong immunoreactivity in the molecular layer. -
Gene Info — AQP4
Entrez GeneID
361Protein Accession#
P55087Gene Name
AQP4
Gene Alias
HMIWC2, MGC22454, MIWC
Gene Description
aquaporin 4
Omim ID
600308Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
aquaporin type4|aquaporin-4|mercurial-insensitive water channel
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Interactome
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Disease
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