ITGAE monoclonal antibody, clone Ber-ACT8 (FITC)
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Specification
Product Description
Mouse monoclonal antibody raised against native human ITGAE.
Immunogen
HTLV-1 induced human T cell line MAPS16.
Host
Mouse
Theoretical MW (kDa)
25-150
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (20 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — ITGAE
Entrez GeneID
3682Protein Accession#
P38570Gene Name
ITGAE
Gene Alias
CD103, HUMINAE, MGC141996
Gene Description
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Omim ID
604682Gene Ontology
HyperlinkGene Summary
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq
Other Designations
HML-1 antigen|antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide|integrin alpha-IEL|integrin, alpha E
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Interactome
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Pathway
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Disease
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