CD63 monoclonal antibody, clone TEA3/18 (PE)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of PMA-activated human peripheral blood platelets (red histogram) and non-activated (green histogram) with CD63 monoclonal antibody, clone TEA3/18 (PE) (Cat # MAB15358).
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Specification
Product Description
Mouse monoclonal antibody raised against human CD63.
Immunogen
Cell preparation of human cytochrome B enriched cells.
Host
Mouse
Theoretical MW (kDa)
53
Reactivity
Human
Form
Liquid
Conjugation
PE
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (20 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
Storage Instruction
Store in the dark at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of PMA-activated human peripheral blood platelets (red histogram) and non-activated (green histogram) with CD63 monoclonal antibody, clone TEA3/18 (PE) (Cat # MAB15358). -
Gene Info — CD63
Entrez GeneID
967Protein Accession#
P08962Gene Name
CD63
Gene Alias
LAMP-3, ME491, MLA1, OMA81H, TSPAN30
Gene Description
CD63 molecule
Omim ID
155740Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq
Other Designations
CD63 antigen|CD63 antigen (melanoma 1 antigen)|granulophysin|lysosome-associated membrane glycoprotein 3|melanoma 1 antigen|melanoma-associated antigen ME491|melanoma-associated antigen MLA1|ocular melanoma-associated antigen|tetraspanin-30
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Interactome
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Pathway
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