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Last updated: 2017/12/17

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CBX1 monoclonal antibody, clone 5A3

  • Catalog # : MAB15261
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human CBX1.
  • Immunogen:
  • Recombinant protein corresponding to human CBX1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Monkey, Mouse
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Immunofluorescence (1:200-1:1000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascitic fluid (0.03% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Lane 1: HeLa, Lane 2: COS7, Lane 3: NIH/3T3, Lane 4: A431 and Lane5: C6 cell lysate.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of HeLa cells using CBX1 monoclonal antibody, clone 5A3 (Green). Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of COS7 cells using CBX1 monoclonal antibody, clone 5A3 (Green) and negative control (Purple).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • CBX1
  • Gene Alias:
  • CBX,HP1-BETA,HP1Hs-beta,HP1Hsbeta,M31,MOD1,p25beta
  • Gene Description:
  • chromobox homolog 1 (HP1 beta homolog Drosophila )
  • Gene Summary:
  • This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
  • Other Designations:
  • heterochromatin protein 1-beta,heterochromatin protein p25 beta,modifier 1 protein
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