TYRP1 monoclonal antibody, clone SPM456
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against native human TYRP1.
Immunogen
SK-MEL-23 cells.
Host
Mouse
Theoretical MW (kDa)
75
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2a, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Frozen sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Frozen sections)
Immunofluorescence
Flow Cytometry
-
Gene Info — TYRP1
Entrez GeneID
7306Protein Accession#
P17643Gene Name
TYRP1
Gene Alias
CAS2, CATB, GP75, TRP, TYRP, b-PROTEIN
Gene Description
tyrosinase-related protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq
Other Designations
associated with iris pigmentation
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.
Hoashi T, Sato S, Yamaguchi Y, Passeron T, Tamaki K, Hearing VJ.
FASEB Journal 2010 May; 24(5):1616.
Application:IF, Human, MNT-1 cells.
-
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
Zhang JG, Eguchi J, Kruse CA, Gomez GG, Fakhrai H, Schroter S, Ma W, Hoa N, Minev B, Delgado C, Wepsic HT, Okada H, Jadus MR.
Clinical Cancer Research 2007 Jan; 13(2 Pt 1):566.
Application:Flow Cyt, Human, U-251 cells.
-
Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com