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Last updated: 2017/10/22

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ITGAM monoclonal antibody, clone SP331

  • Catalog # : MAB15151
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human ITGAM.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human ITGAM.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 170
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:400)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    Western Blot (1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of TF1 cell lysates with ITGAM monoclonal antibody, clone SP331 (Cat # MAB15151).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with ITGAM monoclonal antibody, clone SP331 (Cat # MAB15151).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of TF1 cells with ITGAM monoclonal antibody, clone SP331 (Cat # MAB15151) (Green) compare to negative control of rabbit IgG (Blue)
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3684
  • Gene Name:
  • ITGAM
  • Gene Alias:
  • CD11B,CR3A,MAC-1,MAC1A,MGC117044,MO1A,SLEB6
  • Gene Description:
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • Gene Summary:
  • This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • antigen CD11b (p170),complement component receptor 3, alpha,integrin alpha M,macrophage antigen alpha polypeptide,neutrophil adherence receptor alpha-M subunit
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