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SOX10 monoclonal antibody, clone SP275

  • Catalog # : MAB15142
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human SOX10.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human SOX10.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 56
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:400)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    Western Blot (1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of A375 cell lysates with SOX10 monoclonal antibody, clone SP275 (Cat # MAB15142).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human melanoma and (B) human breast with SOX10 monoclonal antibody, clone SP275 (Cat # MAB15142).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of A375 cells with SOX10 monoclonal antibody, clone SP275 (Cat # MAB15142) (Green) compare to negative control of rabbit IgG (Blue)
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6663
  • Gene Name:
  • SOX10
  • Gene Alias:
  • DOM,MGC15649,WS2E,WS4
  • Gene Description:
  • SRY (sex determining region Y)-box 10
  • Gene Summary:
  • This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028515,OTTHUMP00000195094,SRY-related HMG-box gene 10,dominant megacolon, mouse, human homolog of
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