ACTC1 monoclonal antibody, clone RM257
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of mouse heart tissue lysates with ACTC1 monoclonal antibody, clone RM257 (Cat # MAB15136) at a 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart with ACTC1 monoclonal antibody, clone RM257 (Cat # MAB15136) at a 1:1000 dilution.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against of human ACTC1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to N-terminus of human ACTC1.
Sequence
N/A
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein A affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of mouse heart tissue lysates with ACTC1 monoclonal antibody, clone RM257 (Cat # MAB15136) at a 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart with ACTC1 monoclonal antibody, clone RM257 (Cat # MAB15136) at a 1:1000 dilution. -
Gene Info — ACTC1
Entrez GeneID
70Protein Accession#
P68032Gene Name
ACTC1
Gene Alias
ACTC, CMD1R, CMH11
Gene Description
actin, alpha, cardiac muscle 1
Gene Ontology
HyperlinkGene Summary
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq
Other Designations
cardiac muscle alpha actin 1
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Interactome
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Pathway
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Disease
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