Products

Western Blot

Western blot analysis of Lane 1: recombinant Histone H2A, Lane 2: recombinant Histone H2B, Lane 3: HeLa, Lane 4: A375, Lane 5: SK-MEL-2, Lane 6: A431, Lane 7: K562 whole cell lysates with Histone H2B monoclonal antibody, clone RM230 (Cat # MAB15119) at 0.2 ug/mL working concentration.

Immunocytochemistry

Immunocytochemistry staining of HeLa cells with Histone H2B monoclonal antibody, clone RM230 (Cat # MAB15119) (Red). Actin filaments was labeled with fluorescein phalloidin (Green).

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

8349

Protein Accession#

P06899

Gene Name

HIST2H2BE

Gene Alias

GL105, H2B, H2B.1, H2B/q, H2BFQ, MGC119802, MGC119804, MGC129733, MGC129734

Gene Description

histone cluster 2, H2be

Omim ID

601831

Gene Ontology

Hyperlink

Gene Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq

Other Designations

H2B histone family, member Q|OTTHUMP00000013920|histone 2, H2be