CD48 monoclonal antibody, clone 156-4H9
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Specification
Product Description
Mouse monoclonal antibody raised against native human CD48.
Immunogen
Native purified human CD48.
Host
Mouse
Theoretical MW (kDa)
45
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2a, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Flow Cytometry
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Gene Info — CD48
Entrez GeneID
962Protein Accession#
P09326Gene Name
CD48
Gene Alias
BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48
Gene Description
CD48 molecule
Omim ID
109530Gene Ontology
HyperlinkGene Summary
BLAST1 is the designation used for an activation-associated cell surface glycoprotein of 40 to 45 kD expressed primarily in mitogen-stimulated human lymphocytes. The protein sequence predicted by the cDNA encoding BLAST1 indicates that BLAST1 is a member of the immunoglobulin supergene family. Yokoyama (1991) identified the BLAST1 activation/adhesion molecule as CD48.[supplied by OMIM
Other Designations
CD48 antigen (B-cell membrane protein)|OTTHUMP00000025680|OTTHUMP00000060268
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Interactome
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Pathway
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Disease
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Publication Reference
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Flow cytometric measurement of glycosylphosphatidyl-inositol-linked surface proteins on blood cells of patients with paroxysmal nocturnal hemoglobinuria.
Kwong YL, Lee CP, Chan TK, Chan LC.
American Journal of Clinical Pathology 1994 Jul; 102(1):30.
Application:Flow Cyt, Human, Blood cells, Monocytes.
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CD48 is a low affinity ligand for human CD2.
Sandrin MS, Mouhtouris E, Vaughan HA, Warren HS, Parish CR.
The Journal of Immunology 1993 Nov; 151(9):4606.
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Expression of the Blast-1 activation/adhesion molecule and its identification as CD48.
Yokoyama S, Staunton D, Fisher R, Amiot M, Fortin JJ, Thorley-Lawson DA.
Journal of Immunology 1991 Apr; 146(7):2192.
Application:Flow Cyt, Func, IP, Human, Monkey, B cells, CEM, COS-7, ER-LCL, RAMOS, T cells.
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The isolation of cDNA clones for CD48.
Vaughan HA, Henning MM, Purcell DF, McKenzie IF, Sandrin MS.
Immunogenetics 1991 Feb; 33(2):113.
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Hu Ly-M3--a human leukocyte antigen.
Vaughan HA, Thompson CH, Sparrow RL, McKenzie IF.
Transplantation 1983 Oct; 36(4):446.
Application:Flow Cyt, Func, IP, Human, Human PBL.
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Flow cytometric measurement of glycosylphosphatidyl-inositol-linked surface proteins on blood cells of patients with paroxysmal nocturnal hemoglobinuria.
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