PAX8 monoclonal antibody, clone PAX8/1492
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: recombinant protein and Lane 2: Raji cell lysate with PAX8 monoclonal antibody, clone PAX8/1492 (Cat # MAB15043).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human renal cell carcinoma (A), human thyroid carcinoma (B) and human urothelial carcinoma (C) with PAX8 monoclonal antibody, clone PAX8/1492 (Cat # MAB15043).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PAX8.
Immunogen
Recombinant protein corresponding to amino acids 60-261 of human PAX8.
Host
Mouse
Theoretical MW (kDa)
62
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2a
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western Blot analysis of Lane 1: recombinant protein and Lane 2: Raji cell lysate with PAX8 monoclonal antibody, clone PAX8/1492 (Cat # MAB15043).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human renal cell carcinoma (A), human thyroid carcinoma (B) and human urothelial carcinoma (C) with PAX8 monoclonal antibody, clone PAX8/1492 (Cat # MAB15043).Immunofluorescence
Flow Cytometry
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Gene Info — PAX8
Entrez GeneID
7849Protein Accession#
Q06710Gene Name
PAX8
Gene Alias
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Gene Description
paired box 8
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000158659|OTTHUMP00000158660|paired domain gene 8
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Interactome
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Pathway
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Disease
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Publication Reference
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Expression of PAX8 in normal and neoplastic renal tissues: an immunohistochemical study.
Tong GX, Yu WM, Beaubier NT, Weeden EM, Hamele-Bena D, Mansukhani MM, O'Toole KM.
Modern Pathology 2009 Sep; 22(9):1218.
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Expression of PAX8 in normal and neoplastic renal tissues: an immunohistochemical study.
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