VWF monoclonal antibody, clone F8/86
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Specification
Product Description
Mouse monoclonal antibody raised against native human VWF.
Immunogen
Native purified VWF from human plasma.
Host
Mouse
Theoretical MW (kDa)
250
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with VWF monoclonal antibody, clone F8/86 (Cat # MAB15036).Immunofluorescence
Flow Cytometry
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Gene Info — VWF
Entrez GeneID
7450Protein Accession#
P04275Gene Name
VWF
Gene Alias
F8VWF, VWD
Gene Description
von Willebrand factor
Omim ID
193400Gene Ontology
HyperlinkGene Summary
The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq
Other Designations
coagulation factor VIII VWF
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Interactome
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Pathway
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Disease
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Publication Reference
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Silk fibroin processing and thrombogenic responses.
Motta A, Maniglio D, Migliaresi C, Kim HJ, Wan X, Hu X, Kaplan DL.
Journal of Biomaterials Science. Polymer Edition 2009 Jan; 20(13):1875.
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Applying blood-brain barrier in vitro models to study the influence of drugs on endothelial cells--effects of selected COX-inhibitors.
Germann B, Neuhaus W, Hofer-Warbinek R, Noe CR.
Die Pharmazie 2008 Apr; 63(4):303.
Application:ELISA, IF, WB-Ce, Bovine, Human, ECV304, HUVECs, PBMEC/C1-2, VCAM-1.
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Silk fibroin processing and thrombogenic responses.
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