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THBD monoclonal antibody, clone THBD/1591

  • Catalog # : MAB15007
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human THBD.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 69-194 of human THBD.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • ~100
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • ELISA (2-4 ug/mL for coating)
    Flow Cytometry (0.5-1 ug/106 cells)
    Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    Western Blotting (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of Lane 1: recombinant protein and Lane 2: THP1 cell lysate with THBD monoclonal antibody, clone THBD/1591 (Cat # MAB15007).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervical carcinoma (A), human bladder carcinoma (B) and human placenta (C) with THBD monoclonal antibody, clone THBD/1591 (Cat # MAB15007).
  • Immunofluorescence
  • ELISA
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • ELISA
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7056
  • Gene Name:
  • THBD
  • Gene Alias:
  • CD141,THRM,TM
  • Gene Description:
  • thrombomodulin
  • Gene Summary:
  • The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq
  • Other Designations:
  • CD141 antigen,OTTHUMP00000030415,fetomodulin
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