Mouse monoclonal antibody raised against partial recombinant human THBD.
Recombinant protein corresponding to amino acids 69-194 of human THBD.
Theoretical MW (kDa):
Protein A/G purification
ELISA (2-4 ug/mL for coating) Flow Cytometry (0.5-1 ug/106 cells) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) Western Blotting (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
In 10 mM PBS.
Store at -20 to -80°C. Aliquot to avoid repeated freezing and thawing.
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervical carcinoma (A), human bladder carcinoma (B) and human placenta (C) with THBD monoclonal antibody, clone THBD/1591 (Cat # MAB15007).
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq