Mouse monoclonal antibody raised against partial recombinant human SOX2.
Recombinant protein corresponding to amino acids 176-305 of human SOX2.
Theoretical MW (kDa):
Protein A/G purification
ELISA (2-4 ug/mL for coating) Flow Cytometry (0.5-1 ug/106 cells) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blotting (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
In 10 mM PBS.
Store at -20 to -80°C. Aliquot to avoid repeated freezing and thawing.
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq
SRY-related HMG-box gene 2,sex-determining region Y-box 2,transcription factor SOX2