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CASP7 monoclonal antibody, clone SP284

  • Catalog # : MAB14906
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CASP7.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human CASP7.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    Western Blot (1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate) analysis of Jurkat cell with CASP7 monoclonal antibody, clone SP284 (Cat # MAB14906).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil (A), human endometrial adenocarcinoma (B), human breast ductal carcinoma (C,D) and human lung adenocarcinoma (E) with CASP7 monoclonal antibody, clone SP284 (Cat # MAB14906).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 840
  • Gene Name:
  • CASP7
  • Gene Alias:
  • CMH-1,ICE-LAP3,MCH3
  • Gene Description:
  • caspase 7, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq
  • Other Designations:
  • ICE-like apoptotic protease 3,Lice2 alpha/beta/gamma,OTTHUMP00000020510,OTTHUMP00000020511,OTTHUMP00000020512,OTTHUMP00000020514,apoptotic protease MCH-3,caspase 7,caspase 7 isoform delta,caspase 7, apoptosis-related cysteine protease
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