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Last updated: 2017/3/26
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VCL monoclonal antibody, clone VIN-54

  • Catalog # : MAB1490
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native VCL.
  • Immunogen:
  • Native purified human uterus VCL.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 116
  • Reactivity:
  • Chicken, Human, Mouse, Rat
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunohistochemistry (Frozen section) (2-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 1.2% sodium acetate (2 mg BSA, 0.01 mg sodium azide)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 7414
  • Gene Name:
  • VCL
  • Gene Alias:
  • CMD1W,MVCL
  • Gene Description:
  • vinculin
  • Gene Summary:
  • Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019861,OTTHUMP00000043885,metavinculin
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