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Last updated: 2017/10/15

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TIA1 monoclonal antibody, clone TIA1/1313

  • Catalog # : MAB14897
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human TIA1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 279-380 of human TIA1 (exact sequence is proprietary).
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/million cells)
    Immunofluorescence (1-2 ug/mL)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA and 0.05% azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate) analysis with TIA1 monoclonal antibody, clone TIA1/1313 (Cat # MAB14897):
    1. HepG2 cell line
    2. PC3 cell line
    3. HeLa cell line
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7072
  • Gene Name:
  • TIA1
  • Gene Alias:
  • -
  • Gene Description:
  • TIA1 cytotoxic granule-associated RNA binding protein
  • Gene Summary:
  • The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq
  • Other Designations:
  • T-cell-restricted intracellular antigen-1,TIA1 cytotoxic granule-associated RNA-binding protein,TIA1 protein,cytotoxic granule-associated RNA-binding protein,nucleolysin TIA-1 isoform p40,p40-TIA-1 (containing p15-TIA-1)
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