ANO1 monoclonal antibody, clone DG1/1484
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gastrointestinal stromal tumor with ANO1 monoclonal antibody, clone DG1/1484 (Cat # MAB14888).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ANO1.
Immunogen
Recombinant protein corresponding to amino acids 2-101 of human ANO1.
Host
Mouse
Theoretical MW (kDa)
~114
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gastrointestinal stromal tumor with ANO1 monoclonal antibody, clone DG1/1484 (Cat # MAB14888).Immunofluorescence
Flow Cytometry
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Gene Info — ANO1
Entrez GeneID
55107Protein Accession#
Q5XXA6Gene Name
ANO1
Gene Alias
FLJ10261, ORAOV2, TAOS2, TMEM16A
Gene Description
anoctamin 1, calcium activated chloride channel
Omim ID
610108Gene Ontology
HyperlinkGene Summary
O
Other Designations
membrane protein|oral cancer overexpressed 2|transmembrane protein 16A|transmembrane protein 16A (eight membrane-spanning domains)|tumor amplified and overexpressed sequence 2
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Interactome
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Disease
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Publication Reference
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A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors.
Espinosa I, Lee CH, Kim MK, Rouse BT, Subramanian S, Montgomery K, Varma S, Corless CL, Heinrich MC, Smith KS, Wang Z, Rubin B, Nielsen TO, Seitz RS, Ross DT, West RB, Cleary ML, van de Rijn M.
The American Journal of Surgical Pathology 2008 Feb; 32(2):210.
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A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors.
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