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Last updated: 2017/6/25

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NOX4 monoclonal antibody, clone NOX4/1245

  • Catalog # : MAB14858
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human NOX4.
  • Immunogen:
  • Recombinant protein corresponding to full length human NOX4.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 70
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • ELISA
    Flow Cytometry (0.5-1 ug/106 cells)
    Immunofluorescence (0.5-1 ug/mL)
    Western Blotting (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunofluorescence
  • ELISA
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunofluorescence
  • ELISA
  • Flow Cytometry
  • Gene Information
  • Gene Name:
  • NOX4
  • Gene Alias:
  • KOX,KOX-1,RENOX
  • Gene Description:
  • NADPH oxidase 4
  • Gene Summary:
  • This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants
  • Other Designations:
  • kidney superoxide-producing NADPH oxidase,renal NAD(P)H-oxidase
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