GJB1 monoclonal antibody, clone GJB1/1753
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver (A) and human tonsil (B) with GJB1 monoclonal antibody, clone GJB1/1753 (Cat # MAB14802).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human GJB1.
Immunogen
Recombinant protein corresponding to full length human GJB1.
Host
Mouse
Theoretical MW (kDa)
27-32
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver (A) and human tonsil (B) with GJB1 monoclonal antibody, clone GJB1/1753 (Cat # MAB14802).Immunofluorescence
Flow Cytometry
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Gene Info — GJB1
Entrez GeneID
2705Protein Accession#
P08034Gene Name
GJB1
Gene Alias
CMTX, CMTX1, CX32
Gene Description
gap junction protein, beta 1, 32kDa
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023502|OTTHUMP00000023503|OTTHUMP00000023504|connexin 32
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Interactome
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Disease
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Publication Reference
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Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions.
Goodenough DA, Paul DL, Jesaitis L.
The Journal of Cell Biology 1988 Nov; 107(5):1817.
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Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions.
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