FAT2 monoclonal antibody, clone 8C5
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervical carcinoma (A) and human bladder carcinoma (B) with FAT2 monoclonal antibody, clone 8C5 (Cat # MAB14781).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human FAT2.
Immunogen
Recombinant protein corresponding to full length human FAT2.
Host
Mouse
Theoretical MW (kDa)
480
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervical carcinoma (A) and human bladder carcinoma (B) with FAT2 monoclonal antibody, clone 8C5 (Cat # MAB14781).Immunofluorescence
Flow Cytometry
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Gene Info — FAT2
Entrez GeneID
2196Protein Accession#
Q9NYQ8Gene Name
FAT2
Gene Alias
CDHF8, HFAT2, MEGF1
Gene Description
FAT tumor suppressor homolog 2 (Drosophila)
Omim ID
604269Gene Ontology
HyperlinkGene Summary
This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq
Other Designations
FAT tumor suppressor 2|cadherin family member 8|multiple epidermal growth factor-like domains 1|protocadherin FAT2
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Interactome
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Publication Reference
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Recent progress in protocadherin research.
Suzuki ST.
Experimental Cell Research 2000 Nov; 261(1):13.
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Protocadherins: a large family of cadherin-related molecules in central nervous system.
Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S.
The EMBO Journal 1993 Jun; 12(6):2249.
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Recent progress in protocadherin research.
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