ETS1 monoclonal antibody, clone ETS1/1282
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with ETS1 monoclonal antibody, clone ETS1/1282 (Cat # MAB14775).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ETS1.
Immunogen
Recombinant protein corresponding to amino acids 137-230 of human ETS1.
Host
Mouse
Theoretical MW (kDa)
54
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blotting (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with ETS1 monoclonal antibody, clone ETS1/1282 (Cat # MAB14775).Immunofluorescence
Flow Cytometry
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Gene Info — ETS1
Entrez GeneID
2113Protein Accession#
P14921Gene Name
ETS1
Gene Alias
ETS-1, EWSR2, FLJ10768
Gene Description
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
Omim ID
164720Gene Ontology
HyperlinkGene Summary
ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM
Other Designations
Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1|ets protein|v-ets avian erythroblastosis virus E2 oncogene homolog 1|v-ets avian erythroblastosis virus E26 oncogene homolog 1|v-ets erythroblastosis virus E26 oncogene homolog 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Immunohistochemical expression of Ets-1 transcription factor and the urokinase-type plasminogen activator is correlated with the malignant and invasive potential in meningiomas.
Kitange G, Tsunoda K, Anda T, Nakamura S, Yasunaga A, Naito S, Shibata S.
Cancer 2000 Dec; 89(11):2292.
Application：IHC-P, WB-Ti, Human, Human meningiomas.
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Immunohistochemical expression of Ets-1 transcription factor and the urokinase-type plasminogen activator is correlated with the malignant and invasive potential in meningiomas.
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