Cdkn1b monoclonal antibody, clone DCS-72
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant Cdkn1b.
Immunogen
Recombinant protein corresponding to full length rodent Cdkn1b.
Host
Mouse
Theoretical MW (kDa)
22
Reactivity
Human, Mouse, Rat, Rodents
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 1.2% sodium acetate (2 mg BSA, 0.01 mg sodium azide)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunocytochemistry
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Publication Reference
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A polymorphism in the CDKN1B gene is associated with increased risk of hereditary prostate cancer.
Chang BL, Zheng SL, Isaacs SD, Wiley KE, Turner A, Li G, Walsh PC, Meyers DA, Isaacs WB, Xu J.
Cancer Research 2004 Mar; 64(6):1997.
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A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase.
Malek NP, Sundberg H, McGrew S, Nakayama K, Kyriakides TR, Roberts JM.
Nature 2001 Sep; 413(6853):323.
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Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells.
Mitsuhashi T, Aoki Y, Eksioglu YZ, Takahashi T, Bhide PG, Reeves SA, Caviness VS Jr.
PNAS 2001 May; 98(11):6435.
Application:WB-Ti, Mouse, Mouse forebrains.
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A polymorphism in the CDKN1B gene is associated with increased risk of hereditary prostate cancer.
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