Mouse monoclonal antibody raised against partial recombinant human CDX2.
Recombinant protein corresponding to amino acids 150-249 of human CDX2.
Theoretical MW (kDa):
Protein A/G purification
ELISA (2-4 ug/mL for coating) Flow Cytometry (0.5-1 ug/106 cells) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
In 10 mM PBS.
Store at -20 to -80°C. Aliquot to avoid repeated freezing and thawing.
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
OTTHUMP00000018176,caudal type homeo box transcription factor 2,caudal type homeobox transcription factor 2