NAPSA monoclonal antibody, clone NAPSA/1239
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis with NAPSA monoclonal antibody, clone NAPSA/1239 (Cat # MAB14709):
1. K562 cell line
2. HEK293 cell line
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung adenocarcinoma with NAPSA monoclonal antibody, clone NAPSA/1239 (Cat # MAB14709).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human NAPSA.
Immunogen
Recombinant protein corresponding to human NAPSA.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis with NAPSA monoclonal antibody, clone NAPSA/1239 (Cat # MAB14709):
1. K562 cell line
2. HEK293 cell lineImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung adenocarcinoma with NAPSA monoclonal antibody, clone NAPSA/1239 (Cat # MAB14709).Immunofluorescence
Flow Cytometry
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Gene Info — NAPSA
Entrez GeneID
9476Protein Accession#
O96009Gene Name
NAPSA
Gene Alias
KAP, Kdap, NAP1, NAPA, SNAPA
Gene Description
napsin A aspartic peptidase
Omim ID
605631Gene Ontology
HyperlinkGene Summary
The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq
Other Designations
napsin A|pronapsin A
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Interactome
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Pathway
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Publication Reference
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Napsin A expression in lung and kidney neoplasia: a review and update.
Nelson G Ordonez.
Advances in Anatomic Pathology 2012 Jan; 19(1):66.
Application：IHC-P, Human, Human lung adenocarcinomas, Human renal cell carcinomas.
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Combination of napsin A and TTF-1 immunohistochemistry helps in differentiating primary lung adenocarcinoma from metastatic carcinoma in the lung.
Jiqing Ye, Jennifer J Findeis-Hosey, Qi Yang, Loralee A McMahon, Jorge L Yao, Faqian Li, Haodong Xu.
Applied Immunohistochemistry & Molecular Morphology 2011 Jul; 19(4):313.
Application：IHC-P, Human, Human lung adenocarcinoma, Human renal cell carcinomas, Human tissue microarray.
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Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma.
Justin A Bishop, Rajni Sharma, Peter B Illei.
Human Pathology 2010 Jan; 41(1):20.
Application：IHC-P, Human, Human tissue microarray.
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Napsin A expression in lung and kidney neoplasia: a review and update.
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