Product Browser

Last updated: 2022/5/22

Related Product Showcase

By Application

Product Compare

Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Where to buy
Choose your location

Bulk order

Custom Services

2019 Next Day Shipping

MYADM monoclonal antibody, clone MYADM/972

Catalog # : MAB14707
Visit Frequency :

Countries :

Interested in larger quantities? Request a quote!

Need help with custom service projects?

Get $500 voucher for order over USD $5,000 in a year.

Specification

Product Description:
Mouse monoclonal antibody raised against human MYADM.

Immunogen:
Recombinant protein corresponding to human MYADM.

Host:
Mouse

Reactivity:
Human

Specificity:
Recognizes a myeloid associated differentiation antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues.

Form:
Liquid

Purification:
Protein A/G purification

Isotype:
IgG1, kappa

Recommend Usage:
Flow Cytometry (1-2 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
The optimal working dilution should be determined by the end user.

Storage Buffer:
In 10 mM PBS.

Storage Instruction:
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.

Datasheet:
Download

Publication Reference

1.
MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression.
Aranda JF, Reglero-Real N, Marcos-Ramiro B, Ruiz-Sáenz A, Fernández-Martín L, Bernabé-Rubio M, Kremer L, Ridley AJ, Correas I, Alonso MA, Millán J.Mol Biol Cell. 2013 Feb;24(4):483-94. doi: 10.1091/mbc.E11-11-0914. Epub 2012 Dec 21.

2.
MYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migration.
Aranda JF, Reglero-Real N, Kremer L, Marcos-Ramiro B, Ruiz-Sáenz A, Calvo M, Enrich C, Correas I, Millán J, Alonso MA.Mol Biol Cell. 2011 Apr 15;22(8):1252-62. doi: 10.1091/mbc.E10-11-0910. Epub 2011 Feb 16.

3.
Membrane protein hMYADM preferentially expressed in myeloid cells is up-regulated during differentiation of stem cells and myeloid leukemia cells.
Wang Q, Li N, Wang X, Shen J, Hong X, Yu H, Zhang Y, Wan T, Zhang L, Wang J, Cao X.Life Sci. 2007 Jan 9;80(5):420-9. Epub 2006 Oct 14.

4.
Cloning of human myeloid-associated differentiation marker (MYADM) gene whose expression was up-regulated in NB4 cells induced by all-trans retinoic acid.
Cui W, Yu L, He H, Chu Y, Gao J, Wan B, Tang L, Zhao S.Mol Biol Rep. 2001;28(3):123-38.

5.
Isolation of MYADM, a novel hematopoietic-associated marker gene expressed in multipotent progenitor cells and up-regulated during myeloid differentiation.
Pettersson M, Dannaeus K, Nilsson K, Jönsson JI.J Leukoc Biol. 2000 Mar;67(3):423-31.

Applications

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with MYADM monoclonal antibody, clone MYADM/972 (Cat # MAB14707).

Immunofluorescence

Flow Cytometry

Application Image

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge

Immunofluorescence

Flow Cytometry

Gene Information

Entrez GeneID:
91663

Protein Accession#:
Q96S97

Gene Name:
MYADM

Gene Alias:
SB135

Gene Description:
myeloid-associated differentiation marker

Omim ID:
609959

Gene Ontology:
Hyperlink

Other Designations:
myeloid upregulated protein

Related Product

MAB14420
MYADM monoclonal antibody, clone MYADM/971

MAB14421
MYADM monoclonal antibody, clone MYADM/972

MAB14656
MYADM monoclonal antibody, clone MYADM/971