Mouse monoclonal antibody raised against partial recombinant human ITGAX.
Immunogen:
Recombinant protein corresponding to amino acids 637-827 of human ITGAX (exact sequence is proprietary).
Host:
Mouse
Theoretical MW (kDa):
145
Reactivity:
Human
Form:
Liquid
Purification:
Protein A/G purification
Isotype:
IgG2b, kappa
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS.
Storage Instruction:
Store at -20 to -80°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq