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ITGAX monoclonal antibody, clone ITGAX/1242 

  • Catalog # : MAB14686
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human ITGAX.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 637-827 of human ITGAX (exact sequence is proprietary).
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 145
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes))
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with ITGAX monoclonal antibody, clone ITGAX/1242 (Cat # MAB14686).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3687
  • Gene Name:
  • ITGAX
  • Gene Alias:
  • CD11C,SLEB6
  • Gene Description:
  • integrin, alpha X (complement component 3 receptor 4 subunit)
  • Gene Summary:
  • This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000163299,integrin alpha X,integrin, alpha X (antigen CD11C (p150), alpha polypeptide),leu M5, alpha subunit,leukocyte surface antigen p150,95, alpha subunit,myeloid membrane antigen, alpha subunit,p150 95 integrin alpha chain
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