Macrophage and Histiocytoma monoclonal antibody, clone D11
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Specification
Product Description
Mouse monoclonal antibody raised against human macrophage and histiocytoma.
Immunogen
Membrane preparation from human hepatocytes.
Host
Mouse
Theoretical MW (kDa)
125-135
Reactivity
Human
Specificity
This antibody shows a restricted reactivity to cells of the monocyte/macrophage system and specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues.
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS.
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human histiocytoma with Macrophage and Histiocytoma monoclonal antibody, clone D11 (Cat # MAB14670). -
Publication Reference
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Antimacrophage monoclonal antibody D11 in the diagnosis of tumors of histiocytic origin.
Petrovichev NN, Chistyakova OV, Smirnov AV, Poltoranina VS, Rudinskaya TD.
Acta Cytologica 1997 Mar; 41(2):357.
Application:IHC-Fr, Human, Fibrous histiocytoma, Osteosarcoma.
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Reactivity of anti-macrophage monoclonal antibody D11 in human leukemia and malignant lymphoma.
Tupitsyn NN, Frenkel MA, Rudinskaya TD, Poltoranina VS, Sholokhova EN, Lebedeva NB, Probatova NA, Zabotina TN, Shipova LYa.
International Journal of Cancer 1996 Oct; 68(2):160.
Application:WB-Ti, Human, Spleen cells.
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Use of a new antimacrophage monoclonal antibody D11 in diagnosis of hemoblastosis.
Frenkel' MA, Tupitsyn NN, Rudinskaia TD, Poltoranina VS, Lebedeva NB, Volkova MA, Kaletin GI.
Gematol Transfuziol 1995 Jul; 40(4):13.
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D11, a novel monoclonal antibody specific for human mature macrophages and peripheral blood monocytes.
Rudinskaya TD, Poltoranina VS, Baranov VN, Petrovichev NN, Voytenkov BO, Tretyakov LO.
Immunology Letters 1992 Jun; 33(1):1.
Application:IHC-Fr, IHC-P, WB-Ti, Human, Colon Livers, Kidneys, Macrophages, Monocytes.
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Antimacrophage monoclonal antibody D11 in the diagnosis of tumors of histiocytic origin.
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