UCHL1 monoclonal antibody, clone UCHL1/775
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) rat testis and (B) rat cerebellum with UCHL1 monoclonal antibody, clone UCHL1/775 (Cat # MAB14626).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human UCHL1.
Immunogen
Recombinant protein corresponding to full length human UCHL1.
Host
Mouse
Theoretical MW (kDa)
20-30
Reactivity
Human, Rat
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) rat testis and (B) rat cerebellum with UCHL1 monoclonal antibody, clone UCHL1/775 (Cat # MAB14626). -
Gene Info — UCHL1
Entrez GeneID
7345Protein Accession#
P09936Gene Name
UCHL1
Gene Alias
PARK5, PGP9.5, Uch-L1
Gene Description
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease
Other Designations
ubiquitin C-terminal esterase L1|ubiquitin carboxyl-terminal esterase L1|ubiquitin thiolesterase L1
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Interactome
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Disease
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Publication Reference
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The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase.
K D Wilkinson, K M Lee, S Deshpande, P Duerksen-Hughes, J M Boss, J Pohl.
Science 1989 Nov; 46(4930):670.
Application：AFC, WB-Re, WB-Ti, Bovine, Bovine thymus, Recombinant proteins.
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The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase.
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