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SUMO1 monoclonal antibody, clone SUMO1/1188

  • Catalog # : MAB14625
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human SUMO1.
  • Immunogen:
  • Recombinant protein corresponding to full length human SUMO1.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 11.5, 90
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is specific to SUMO1 and shows no cross-reaction with either SUMO2 or SUMO3.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
    Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human ovarian carcinoma (B) human testicular carcinoma (C)(D) human tonsil and (E) rat pancreas with SUMO1 monoclonal antibody, clone SUMO1/1188 (Cat # MAB14625).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7341
  • Gene Name:
  • SUMO1
  • Gene Alias:
  • DAP-1,GMP1,OFC10,PIC1,SENP2,SMT3,SMT3C,SMT3H3,SUMO-1,UBL1
  • Gene Description:
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq
  • Other Designations:
  • GAP modifying protein 1,SMT3 suppressor of mif two 3 homolog 1,sentrin,ubiquitin-like 1 (sentrin)
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