Mouse monoclonal antibody raised against full length recombinant human SUMO1.
Recombinant protein corresponding to full length human SUMO1.
Theoretical MW (kDa):
This antibody is specific to SUMO1 and shows no cross-reaction with either SUMO2 or SUMO3.
Protein A/G purification
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
In 10 mM PBS.
Store at -20 to -80°C. Aliquot to avoid repeated freezing and thawing.
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human ovarian carcinoma (B) human testicular carcinoma (C)(D) human tonsil and (E) rat pancreas with SUMO1 monoclonal antibody, clone SUMO1/1188 (Cat # MAB14625).
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq
GAP modifying protein 1,SMT3 suppressor of mif two 3 homolog 1,sentrin,ubiquitin-like 1 (sentrin)