SUMO1 monoclonal antibody, clone SUMO1/1188
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human ovarian carcinoma (B) human testicular carcinoma (C)(D) human tonsil and (E) rat pancreas with SUMO1 monoclonal antibody, clone SUMO1/1188 (Cat # MAB14625).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human SUMO1.
Immunogen
Recombinant protein corresponding to full length human SUMO1.
Host
Mouse
Theoretical MW (kDa)
11.5, 90
Reactivity
Human, Rat
Specificity
This antibody is specific to SUMO1 and shows no cross-reaction with either SUMO2 or SUMO3.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human ovarian carcinoma (B) human testicular carcinoma (C)(D) human tonsil and (E) rat pancreas with SUMO1 monoclonal antibody, clone SUMO1/1188 (Cat # MAB14625).Immunofluorescence
Flow Cytometry
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Gene Info — SUMO1
Entrez GeneID
7341Protein Accession#
P63165Gene Name
SUMO1
Gene Alias
DAP-1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, SUMO-1, UBL1
Gene Description
SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
Omim ID
601912Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq
Other Designations
GAP modifying protein 1|SMT3 suppressor of mif two 3 homolog 1|sentrin|ubiquitin-like 1 (sentrin)
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Interactome
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Disease
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