Mouse monoclonal antibody raised against full length recombinant human TGFA.
Immunogen:
Recombinant protein corresponding to full length human TGM2.
Host:
Mouse
Theoretical MW (kDa):
77-85
Reactivity:
Human
Form:
Liquid
Purification:
Protein A/G purification
Isotype:
IgG2a, kappa
Recommend Usage:
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM PBS.
Storage Instruction:
Store at -20 to -80°C. Aliquot to avoid repeated freezing and thawing.
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human tonsil (B) human placenta (C) human uterus and (D) human leiomyosarcoma with TGM2 monoclonal antibody, clone SPM358 (Cat # MAB14616).
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations:
C polypeptide,OTTHUMP00000030960,TGase C,TGase-H,protein-glutamine-gamma-glutamyltransferase,tissue transglutaminase,transglutaminase 2,transglutaminase C