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TGM2 monoclonal antibody, clone TGM2/419

  • Catalog # : MAB14616
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human TGFA.
  • Immunogen:
  • Recombinant protein corresponding to full length human TGM2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 77-85
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
    Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human tonsil (B) human placenta (C) human uterus and (D) human leiomyosarcoma with TGM2 monoclonal antibody, clone TGM2/419 (Cat # MAB14616).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7052
  • Gene Name:
  • TGM2
  • Gene Alias:
  • G-ALPHA-h,GNAH,TG2,TGC
  • Gene Description:
  • transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • Gene Summary:
  • Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • C polypeptide,OTTHUMP00000030960,TGase C,TGase-H,protein-glutamine-gamma-glutamyltransferase,tissue transglutaminase,transglutaminase 2,transglutaminase C
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