TFF1 monoclonal antibody, clone TFF1/1091
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human breast carcinoma and (B) human ovarian carcinoma with TFF1 monoclonal antibody, clone TFF1/1091 (Cat # MAB14611).
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human TFF1.
Immunogen
A synthetic peptide corresponding to C-terminus of human TFF1.
Host
Mouse
Theoretical MW (kDa)
6.5
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human breast carcinoma and (B) human ovarian carcinoma with TFF1 monoclonal antibody, clone TFF1/1091 (Cat # MAB14611).Immunofluorescence
Flow Cytometry
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Gene Info — TFF1
Entrez GeneID
7031Protein Accession#
P04155Gene Name
TFF1
Gene Alias
BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2
Gene Description
trefoil factor 1
Omim ID
113710Gene Ontology
HyperlinkGene Summary
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq
Other Designations
breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2
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Interactome
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Disease
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Publication Reference
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Characterization of monoclonal antibodies raised to C-terminal peptides of pS2: a major trefoil peptide and motility factor expressed in adenocarcinomas and regions of mucosal injury.
Williams R, Elia G, Stamp GW, Oates T, Wright NA, Lalani EN.
Human Pathology 1996 Dec; 27(12):1259.
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Characterization of monoclonal antibodies raised to C-terminal peptides of pS2: a major trefoil peptide and motility factor expressed in adenocarcinomas and regions of mucosal injury.
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