Mouse monoclonal antibody raised against partial recombinant human SOX10.
Recombinant protein corresponding to amino acids 115-269 of human SOX10.
Theoretical MW (kDa):
Recognizes a protein of ~55 kDa, identified as SOX10. This antibody is highly specific and does not cross-react with other members of the SOX-family.
Protein A/G purification
Flow Cytometry (0.5-1 ug/million cells) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
In 10 mM PBS.
Store at -20 to -80°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq
OTTHUMP00000028515,OTTHUMP00000195094,SRY-related HMG-box gene 10,dominant megacolon, mouse, human homolog of