ITGB3 monoclonal antibody, clone ITGB3/1713
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human ITGB3.
Immunogen
Recombinant protein corresponding to full length human ITGB3.
Host
Mouse
Theoretical MW (kDa)
105, 90
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Immunohistochemistry (Frozen sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with ITGB3 monoclonal antibody, clone ITGB3/1713 (Cat # MAB14569).Immunohistochemistry (Frozen sections)
Immunofluorescence
Flow Cytometry
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Gene Info — ITGB3
Entrez GeneID
3690Protein Accession#
P05106Gene Name
ITGB3
Gene Alias
CD61, GP3A, GPIIIa
Gene Description
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Omim ID
173470Gene Ontology
HyperlinkGene Summary
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq
Other Designations
integrin beta chain, beta 3|platelet glycoprotein IIIa
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Interactome
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Pathway
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Disease
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Publication Reference
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The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.
Gatter KC, Cordell JL, Turley H, Heryet A, Kieffer N, Anstee DJ, Mason DY.
Histopathology 1988 Sep; 13(3):257.
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The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.
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