FOXA1 monoclonal antibody, clone FOXA1/1515
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human FOXA1.
Immunogen
Recombinant protein corresponding to amino acids 467-614 of human FOXA1.
Host
Mouse
Theoretical MW (kDa)
79
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate carcinoma (A, B) with FOXA1 monoclonal antibody, clone FOXA1/1515 (Cat # MAB14557).Immunofluorescence
Flow Cytometry
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Gene Info — FOXA1
Entrez GeneID
3169Protein Accession#
P55317Gene Name
FOXA1
Gene Alias
HNF3A, MGC33105, TCF3A
Gene Description
forkhead box A1
Omim ID
602294Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq
Other Designations
hepatocyte nuclear factor 3, alpha
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Interactome
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Disease
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Publication Reference
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Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours.
Andre Albergaria, Joana Paredes, Barbara Sousa, Fernanda Milanezi, Vítor Carneiro, Joana Bastos, Sandra Costa, Daniella Vieira, Nair Lopes, Eric W Lam, Nuno Lunet, Fernando Schmitt.
Breast Cancer Research 2009 Jun; 11(3):R40.
Application:IHC-P, Human, Human breast carcinomas.
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Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours.
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