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FAT2 monoclonal antibody, clone 8C5

  • Catalog # : MAB14525
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human FAT2.
  • Immunogen:
  • Recombinant protein corresponding to full length human FAT2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 480
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervical carcinoma (A) and human bladder carcinoma (B) with FAT2 monoclonal antibody, clone 8C5 (Cat # MAB14525).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 2196
  • Gene Name:
  • FAT2
  • Gene Alias:
  • CDHF8,HFAT2,MEGF1
  • Gene Description:
  • FAT tumor suppressor homolog 2 (Drosophila)
  • Gene Summary:
  • This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq
  • Other Designations:
  • FAT tumor suppressor 2,cadherin family member 8,multiple epidermal growth factor-like domains 1,protocadherin FAT2
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