EPO monoclonal antibody, clone EPO/1368
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More Files
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Western Blot
Western Blot analysis of Lane 1: human heart and Lane 2: HepG2 lysates with EPO monoclonal antibody, clone EPO/1368 (Cat # MAB14518).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human EPO.
Immunogen
Recombinant protein corresponding to amino acids 28-162 of human EPO.
Host
Mouse
Theoretical MW (kDa)
37
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: human heart and Lane 2: HepG2 lysates with EPO monoclonal antibody, clone EPO/1368 (Cat # MAB14518).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunofluorescence
Flow Cytometry
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Gene Info — EPO
Entrez GeneID
2056Protein Accession#
P01588Gene Name
EPO
Gene Alias
EP, MGC138142
Gene Description
erythropoietin
Omim ID
133170Gene Ontology
HyperlinkGene Summary
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq
Other Designations
epoetin
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Interactome
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Pathway
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Disease
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Publication Reference
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Erythropoietin: structure, control of production, and function.
Jelkmann W.
Physiological Reviews 1992 Apr; 72(2):449.
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Erythropoietin: structure, control of production, and function.
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