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ENG monoclonal antibody, clone ENG/1326

  • Catalog # : MAB14512
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human ENG.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 74-251 of human ENG.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 84
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
    Immunofluorescence (1-2 ug/mL)
    Western Blotting (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Lane 1: HeLa, Lane 2: A431 and Lane 3: HL-60 cell lysates with ENG monoclonal antibody, clone ENG/1326 (Cat # MAB14512).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 2022
  • Gene Name:
  • ENG
  • Gene Alias:
  • CD105,END,FLJ41744,HHT1,ORW,ORW1
  • Gene Description:
  • endoglin
  • Gene Summary:
  • This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD105 antigen,OTTHUMP00000022221,Osler-Rendu-Weber syndrome 1
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