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Last updated: 2017/10/15

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DSG3 monoclonal antibody, clone DSG3/1535

  • Catalog # : MAB14506
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human DSG3.
  • Immunogen:
  • Recombinant protein corresponding to extracellular domain of human DSG3.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 130
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    Western Blotting (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung squamous cell carcinoma (A) and human skin (B) with DSG3 monoclonal antibody, clone DSG3/1535 (Cat # MAB14506).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 1830
  • Gene Name:
  • DSG3
  • Gene Alias:
  • CDHF6,DKFZp686P23184,PVA
  • Gene Description:
  • desmoglein 3 (pemphigus vulgaris antigen)
  • Gene Summary:
  • Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq
  • Other Designations:
  • 130-kD pemphigus vulgaris antigen,desmoglein 3,pemphigus vulgaris antigen
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