DES monoclonal antibody, clone DES/1711
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human DES.
Immunogen
Recombinant protein corresponding to full length human DES.
Host
Mouse
Theoretical MW (kDa)
52
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human uterus with DES monoclonal antibody, clone DES/1711 (Cat # MAB14497).Immunofluorescence
Flow Cytometry
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Gene Info — DES
Entrez GeneID
1674Protein Accession#
P17661Gene Name
DES
Gene Alias
CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Gene Description
desmin
Gene Ontology
HyperlinkGene Summary
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq
Other Designations
OTTHUMP00000064865|intermediate filament protein
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Interactome
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Pathway
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Disease
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Publication Reference
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Human desmin-coding gene: complete nucleotide sequence, characterization and regulation of expression during myogenesis and development.
Li ZL, Lilienbaum A, Butler-Browne G, Paulin D.
Gene 1989 May; 78(2):243.
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Human desmin-coding gene: complete nucleotide sequence, characterization and regulation of expression during myogenesis and development.
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