CLTC monoclonal antibody, clone CLTC/1431
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CLTC.
Immunogen
Recombinant protein corresponding to N-terminus of human CLTC.
Host
Mouse
Theoretical MW (kDa)
192
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunofluorescence
Flow Cytometry
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Gene Info — CLTC
Entrez GeneID
1213Protein Accession#
Q00610;P53675Gene Name
CLTC
Gene Alias
CHC, CHC17, CLH-17, CLTCL2, Hc, KIAA0034
Gene Description
clathrin, heavy chain (Hc)
Omim ID
118955Gene Ontology
HyperlinkGene Summary
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq
Other Designations
clathrin heavy chain 1|clathrin, heavy polypeptide (Hc)|clathrin, heavy polypeptide-like 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Structure of human clathrin light chains. Conservation of light chain polymorphism in three mammalian species.
Jackson AP, Parham P.
The Journal of Biological Chemistry 1988 Nov; 263(32):16688.
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Structure of human clathrin light chains. Conservation of light chain polymorphism in three mammalian species.
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